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HLB SPE Cartridge

Extracting apolar to moderately polar acidic, neutral and basic compounds


Finetech® HLB sorbent is composed of monodisperse N-vinylpyrrolidone-divinylbenzene copolymer resin particles, with specific mixture of hydrophilic hydrophobic groups, allowing for retention for a wide range of compounds with very high capacity.

HLB can be used as a general-purpose sorbent, especially for extracting analytes from complicated samples such as blood and urine.

◆ Features:

  • General sorbent, suitable for wide application areas

  • Highly wettable, no worry of bed dryness, rare breakthrough

  • Highly recoveries, excellent reproducibility

  • 3 to 10 times higher adsorption capacity and loadability than C18-bounded silica gel

  • Stable from pH 1 to 14, compatible with common solvents

◆ Specifications:


Surface area: 600 m²/g
Particle size: 40 μm
Pore size: 300 Å

◆ Applications:

  • Determination of drugs, illicit drugs and their metabolites in blood, such as sertraline ibuprofen and heroin

  • Determination of residual antibiotics, catecholamines, and microcystins in foodstuff

  • Determination of veterinary drugs, pesticides and mycotoxin in milk products.

Application: Determination of Quinolones in foods

◆ Chromatographic Conditions

SPE Cartridge: Finetech HLB, 200mg/3mL

System: Waters alliance 2690

Column: Welch Ultimate XB-C18 (4.6*250mm)

Mobile phase A: acetronile

Mobile phase B: water containing 0.1% formic acid

Flowrate: 1 mL/min

Column temperature: room temperature

Injection volume: 20 μL

Detector: UV at 220 nm

◆ Gradient

◆ Results


The results suggest that recoveries of > 80% were obtained by using Finetech's HLB cartridges to extract the four Quinolones in foods.

◆ Ordering Information

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