HLB SPE Cartridge
Extracting apolar to moderately polar acidic, neutral and basic compounds
Finetech® HLB sorbent is composed of monodisperse N-vinylpyrrolidone-divinylbenzene copolymer resin particles, with specific mixture of hydrophilic hydrophobic groups, allowing for retention for a wide range of compounds with very high capacity.
HLB can be used as a general-purpose sorbent, especially for extracting analytes from complicated samples such as blood and urine.
General sorbent, suitable for wide application areas
Highly wettable, no worry of bed dryness, rare breakthrough
Highly recoveries, excellent reproducibility
3 to 10 times higher adsorption capacity and loadability than C18-bounded silica gel
Stable from pH 1 to 14, compatible with common solvents
Surface area: 600 m²/g
Particle size: 40 μm
Pore size: 300 Å
Determination of drugs, illicit drugs and their metabolites in blood, such as sertraline ibuprofen and heroin
Determination of residual antibiotics, catecholamines, and microcystins in foodstuff
Determination of veterinary drugs, pesticides and mycotoxin in milk products.
Application: Determination of Quinolones in foods
◆ Chromatographic Conditions
SPE Cartridge: Finetech HLB, 200mg/3mL
System: Waters alliance 2690
Column: Welch Ultimate XB-C18 (4.6*250mm)
Mobile phase A: acetronile
Mobile phase B: water containing 0.1% formic acid
Flowrate: 1 mL/min
Column temperature: room temperature
Injection volume: 20 μL
Detector: UV at 220 nm
The results suggest that recoveries of > 80% were obtained by using Finetech's HLB cartridges to extract the four Quinolones in foods.